SCUSF 0806: Phase II, Placebo-Controlled Trial of Lisinopril and Coreg CR® to Reduce Cardiotoxicity in Patients with Breast Cancer Receiving (Neo)adjuvant Chemotherapy with Trastuzumab (Herceptin®)

Service: Trial Number:
010-11
Principal Investigator: Conducted at:
Long Beach Memorial, Orange Coast Memorial
Currently enrolling additional patients:
Yes
Age Range:
18 years & up

The purpose of this study is to compare the effects of Lisinopril or Coreg, compared to placebo for the ability to reduce the incidence of Trastuzumab-induced cardiotoxicity. The subject must be a female and greater than 18 years old who is being treated for HER2 positive breast breast cancer which has recurred locally or spread to other parts of the body. This study will tell us which treatment (Lisinopril or Coreg CR), if any, is better at protecting heart function during treatment of breast cancer with Trastuzumab. Three groups of patients will be analyzed: patients who receive Lisinopril, patients who receive Coreg and those that receive placebo only.

MemorialCare Research Center Contact Form

For further information about this study or to express your interest in this study, please fill out and submit this form.
Address
,
 
The email to associate with this registration.