A Randomized Controlled Trial on the Effects of Rate and/or Presence of Dextrose on the Labor Course of Nullilparas

Service: Trial Number:
025-11
Principal Investigator: Conducted at:
Long Beach Memorial, Miller Children's & Women's Hospital Long Beach
Currently enrolling additional patients:
Yes
Age Range:
18 years & up

One of the theories for dysfunctional labor or dystocia, which is the leading indication for primary cesarean delivery, is that uterine forces may not be sufficiently strong to enable a safe vaginal delivery. Even in patients who become completely dilated, poor voluntary muscle effort while pushing results in failed vaginal delivery.  Previous studies have shown that increasing fluid rate or adding dextrose to a standard IV will improve uterine muscle function and delivery outcome. This study will attempt to measure the effects of increasing the rate of IV fluid as well as adding carbohydrate(in the form of a 5% dextrose solution) on labor in woman who are in their first pregnancy. 270 patients in active labor will be assigned to one of three groups each of which will have a different IV dextrose concentration and rate of administration. Various maternal and fetal outcomes will be measured.

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