Office of Statewide Health Planning (OSPHD) Validation Study - Acute Chest and Transfusions in Sickle Cell Disease

Service: Trial Number:
012-11
Principal Investigator: Conducted at:
Long Beach Memorial, Miller Children's & Women's Hospital Long Beach
Currently enrolling additional patients:
Yes
Age Range:
all ages

The leading cause of death of patients with Sickle Cell Disease is a condition called Acute Chest Syndrome which is treated with blood transfusion. The California Office of Statewide Planning (OSHPD) calculated a transfusion rate of 51.9%. This study is a retrospective chart review proposed to validate the OSHPD findings by identifying patients in 3 institutions—Miller Children’s Hospital, Long Beach Memorial Medical Center, and Children’s Hospital of Los Angeles with sickle cell disease and acute chest syndrome and see if the frequency of transfusion is the same as reported by OSHPD as well as look for factors that impact the use of transfusion in this population at high risk of mortality.

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