ECOG 2018: A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer

Service: Trial Number:
116-12
Principal Investigator: Conducted at:
Long Beach Memorial, Orange Coast Memorial
Currently enrolling additional patients:
Yes

The standard treatment for metastatic breast cancer is the use of chemotherapy, anti-hormone pills, or other medications. When the cancer is no longer only in the breast and has spread to other areas of the body, surgery and/or radiation for the tumor in the breast cannot control the other areas of the cancer and are only used if the breast tumor is causing skin breakdown or pain, which happens only in some patients. The purpose of this study is to compare the good and bad effects of a new approach that includes surgery plus radiation for the tumor in the patient’s breast to the standard approach of continued treatment with the medication which is working to control the patient’s tumor. In this study, the patient will receive either surgery plus radiation for the breast, or continue with the best medical treatment advised by the patient’s doctor. About 880 people will take part in this study and will randomly be placed in either of the two groups. The results of the two study arms will be compared.

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